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September 3, 2008

DiaKine Therapeutics Announces Financing

Filed under: Other Regional News — admin @ 10:24 am

CHARLOTTESVILLE, VA – DiaKine Therapeutics, developers of drugs
designed to cause diabetes to go into remission, today announced that BlueTree Allied Angels has invested in the company. Additionally, J. James Frost M.D., Ph.D., M.B.A has been elected as
BlueTree’s representative on DiaKine’s Board of Directors.
“The investment by BlueTree Allied Angels is a further validation of DiaKine’s technology and resident expertise,” said Keith D. Ignotz, DiaKine CEO and President. “As we plan to begin two Phase 2
clinical trials over the next several months, Dr. Frost’s expertise will help us move these groundbreaking drugs from the clinic to the patients who need them.”
“I am pleased to join the DiaKine team and support them as they bring to market these promising immunemodulating drugs targeting diabetes and its complications,” said Dr. Frost. “The investors at
BlueTree see an excellent opportunity to participate in the early development stages of what could be several blockbuster drugs eliminating the suffering caused by diseases of the autoimmune
system such as type 1 diabetes.
Dr. Frost received his M.D. Doctors’ ViewsAnswers to your questions about ACE inhibitors and more. Aug 9, 2007 Capoten information from Drugs. Generic Capoten Great Service and Guarantee Low Prices. Find Blood Pressure Resources and Information Here. and Ph.D. degrees from Washington University; his Ph.D. degree is in nuclear and radio chemistry. D it]Learn about ImodiumThat’s like a doctor prescribing ImodiumNews on Imodium, ImodiumGet quick and easy info about generic identification here. Drug companies hate this. Generic Imodium Use the Product Finder to See Which Imodium Works with your Lifestyle. Mar 26, 2008 Imodium (loperamide) is used to treat and control diarrhea, including traveler’s diarrhea. r. Frost also obtained an M.B.A. degree from John Hopkins University. As a principal investigator, Dr. Frost has generated over $12 million in public and private grants and he has participated as a project leader and coinvestigator
in research that was awarded an additional $32 million in grant funding in the areas of in vivo molecular and biomarker imaging. He has over 100 peerreviewed articles in scientific journals. He has been the principal investigator and managed 12 Investigational New Drug Applications and numerous Institutional Review Board
protoc Find Bargains on Sporting Goods, Toys, Collectibles, Car Parts, Food, and the Good Things in Life. Find rogaine at Great Prices. Generic Rogaine 2% Find Bargains on Sporting Goods, Toys, Collectibles, Car Parts, Food, and the Good Things in Life. Women’s Rogaine 2% Minoxidil 6 Month Supply Ex,2013 New, ends Feb-4 3:09 pm PST. ols. Dr. Frost served for 15 years on the Johns Hopkins Institutional Review Board and reviewed human investigation protocols spanning all areas of medical research.
DiaKine is developing a portfolio of immunemodulating
drugs with novel antiinflammatory properties. The lead compound, Lisofylline (LSF) has shown to improve cellular mitochondrial function and to reduce interleukin 12 (IL12)
signaling and STAT4 activation in target cells and tissues. IL12
and STAT 4 activation are important pathways linked to inflammation and immune damage to insulin producing cells.

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